Rolf W Hartmann Selected Research

2-heptyl-3-hydroxy-4-quinolone

10/2020	Micro-rheological properties of lung homogenates correlate with infection severity in a mouse model of Pseudomonas aeruginosa lung infection.
1/2015	Catechol-based substrates of chalcone synthase as a scaffold for novel inhibitors of PqsD.

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Rolf W Hartmann Research Topics

Disease

20	Breast Neoplasms (Breast Cancer) 04/2016 - 05/2003
19	Prostatic Neoplasms (Prostate Cancer) 01/2019 - 01/2002
17	Heart Failure 01/2017 - 06/2002
16	Fibrosis (Cirrhosis) 01/2017 - 04/2003
15	Neoplasms (Cancer) 01/2019 - 04/2002
12	Infections 10/2022 - 07/2009
12	Endometriosis 09/2019 - 11/2008
11	Cardiovascular Diseases (Cardiovascular Disease) 01/2020 - 10/2006
11	Osteoporosis 09/2019 - 01/2011
8	Cushing Syndrome 01/2019 - 01/2011
6	Hypertension (High Blood Pressure) 11/2020 - 06/2014
5	Prostatic Hyperplasia (Benign Prostatic Hyperplasia) 03/2005 - 01/2002
4	Bone Resorption 01/2019 - 08/2012
4	Pseudomonas Infections 01/2015 - 08/2013
3	Wounds and Injuries (Trauma) 10/2020 - 09/2014
3	Body Weight (Weight, Body) 10/2020 - 10/2006
3	Carcinoma (Carcinomatosis) 06/2010 - 10/2004
2	Bone Fractures (Bone Fracture) 01/2019 - 11/2011
2	Metabolic Diseases (Metabolic Disease) 01/2017 - 08/2011
2	Alzheimer Disease (Alzheimer's Disease) 04/2016 - 12/2014
2	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2015 - 04/2011
2	Hyperaldosteronism (Conn Syndrome) 04/2011 - 06/2002
1	Neglected Diseases 01/2022
1	Schistosomiasis (Bilharziasis) 01/2022
1	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 12/2021
1	Tuberculosis (Tuberculoses) 01/2021
1	Pulmonary Hypertension 11/2020
1	Erectile Dysfunction 11/2020
1	Wound Infection (Wound Infections) 10/2020
1	Adrenocortical Carcinoma 01/2020
1	Hyperplasia 01/2020
1	Renal Cell Carcinoma (Grawitz Tumor) 01/2019
1	Postmenopausal Osteoporosis 01/2019

Drug/Important Bio-Agent (IBA)

21	EnzymesIBA 10/2022 - 01/2002
21	Estrogens (Estrogen)FDA Link 09/2019 - 06/2004
17	Cytochrome P-450 CYP11B2 (CYP11B2)IBA 01/2019 - 06/2002
15	AldosteroneIBA 01/2019 - 06/2002
14	AndrogensIBA 11/2017 - 01/2002
12	Steroid 17-alpha-Hydroxylase (17 alpha Hydroxylase)IBA 01/2019 - 12/2004
11	Oxidoreductases (Dehydrogenase)IBA 12/2021 - 01/2011
11	Steroid 11-beta-Hydroxylase (11 beta-Hydroxylase)IBA 01/2019 - 08/2010
10	Pharmaceutical PreparationsIBA 01/2022 - 03/2003
9	Aromatase (CYP19)IBA 01/2019 - 05/2003
9	Estradiol (Delestrogen)FDA LinkGeneric 01/2019 - 05/2010
7	Hydrocortisone (Cortisol)FDA LinkGeneric 01/2019 - 01/2011
6	Hormones (Hormone)IBA 07/2012 - 06/2004
5	SteroidsIBA 01/2020 - 03/2005
5	abirateroneIBA 11/2017 - 08/2008
4	AcidsIBA 10/2020 - 03/2005
4	Cytochrome P-450 Enzyme System (Cytochrome P450)IBA 01/2019 - 12/2004
4	Testosterone (Sustanon)FDA Link 01/2019 - 01/2012
3	Anti-Bacterial Agents (Antibiotics)IBA 01/2021 - 01/2016
3	Collagenases (Collagenase)FDA Link 01/2020 - 01/2017
3	Estrone FDA Link 09/2019 - 06/2004
3	Estrogen ReceptorsIBA 01/2019 - 06/2004
3	Biological ProductsIBA 01/2019 - 08/2008
3	SaltsIBA 09/2009 - 03/2005
3	PlatinumIBA 03/2007 - 06/2004
2	ZincIBA 10/2022 - 01/2018
2	Virulence Factors (Pathogenicity Factors)IBA 01/2022 - 01/2017
2	Blood Proteins (Serum Proteins)IBA 10/2020 - 06/2004
2	2-heptyl-3-hydroxy-4-quinoloneIBA 10/2020 - 01/2015
2	MineralocorticoidsIBA 01/2020 - 06/2014
2	Aromatase InhibitorsIBA 01/2015 - 01/2013
2	Proteins (Proteins, Gene)FDA Link 01/2014 - 05/2011
2	pyridineIBA 08/2013 - 04/2011
2	ethylenediamine (ethylenediamine dihydroiodide)FDA Link 06/2004 - 06/2004
2	ethyleneIBA 06/2004 - 06/2004
2	DiaminesIBA 06/2004 - 06/2004
1	LactamsIBA 10/2022
1	Carbapenems (Carbapenem Antibiotics)IBA 10/2022
1	Praziquantel (Biltricide)FDA Link 01/2022
1	cytochrome P-450 CYP121IBA 01/2021
1	Celecoxib (Celebrex)FDA Link 11/2020
1	Phosphodiesterase 5 InhibitorsIBA 11/2020
1	Cyclooxygenase 2 Inhibitors (COX-2 Inhibitors)IBA 11/2020
1	Rifampin (Rifampicin)FDA LinkGeneric 10/2020
1	Bacterial RNAIBA 10/2020
1	AlginatesIBA 10/2020
1	clostebolIBA 01/2020
1	Tobramycin (Nebcin)FDA LinkGeneric 01/2020
1	mestanoloneIBA 01/2020
1	HydrogenIBA 01/2020
1	Methenolone (Metenolone)IBA 01/2020
1	ColforsinIBA 01/2020
1	Pseudomonas aeruginosa pseudolysinIBA 01/2020
1	Oxymetholone (Anadrol)FDA Link 01/2020
1	Mesterolone (Proviron)IBA 01/2020
1	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2020
1	Sulfates (Sulfates, Inorganic)IBA 01/2020
1	estradiol 3-benzoate (estradiol benzoate)IBA 01/2019
1	Mixed Function Oxygenases (Monooxygenases)IBA 01/2019
1	silmitasertibIBA 01/2019
1	N-dodecyl-L-lysine amideIBA 01/2019
1	Adenosine Triphosphate (ATP)IBA 01/2019
1	Hydroxysteroid DehydrogenasesIBA 12/2018
1	Protease Inhibitors (Protease Inhibitor)IBA 01/2018

Therapy/Procedure

17	Therapeutics 01/2022 - 04/2003
2	Castration 01/2016 - 07/2013
1	Hormone Replacement Therapy (Therapy, Hormone Replacement) 01/2019